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Korean J Helicobacter  Up Gastrointest Res > Volume 18(4); 2018 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2018;18(4):235-241.
DOI: https://doi.org/10.7704/kjhugr.2018.18.4.235    Published online December 10, 2018.
Endoscopic Hemostatic Treatment of Peptic Ulcer Bleeding
Yeon Hwa Choe, Jun Chul Park 
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. junchul75@yuhs.ac
소화성 궤양 출혈의 내시경 치료
최연화, 박준철
연세대학교 의과대학 내과학교실
Correspondence:  Jun Chul Park, Tel: +82-2-2228-5221, Fax: +82-2-2227-7877, 
Email: junchul75@yuhs.ac
Received: 30 May 2018   • Revised: 24 July 2018   • Accepted: 27 July 2018
Peptic ulcer bleeding is a common complication of peptic ulcer disease and the most common cause of upper gastrointestinal bleeding. Despite advances in drug usage and endoscopic modalities, no significant improvement is observed in the mortality rate of bleeding ulcers. The purpose of this review is to discuss various endoscopic hemostatic methods to treat peptic ulcer bleeding. Endoscopic hemostatic techniques can be classified into injection, mechanical, electrocoagulation, hemostatic powder, and endoscopic Doppler-guided hemostatic therapies (the last mentioned being a newly developed technique). Endoscopic hemostasis can be performed as mono or combination therapy using the aforementioned methods. Endoscopic hemostasis is the most important treatment for patients with peptic ulcer bleeding. Endoscopists should consider the treatment approach for peptic ulcer bleeding based on patient characteristics, the size and shape of the lesion, the endoscopist's expertise, and the resources and circumstances at each hospital. Follow-up studies are needed to evaluate the efficacy of newly developed hemostatic powder therapy and endoscopic Doppler-guided hemostasis.
Key Words: Duodenum; Endoscopic hemostasis; Peptic ulcer hemorrhage; Stomach

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