Current Status and Strategy of <i>Helicobacter</i> <i>pylori </i>Eradication

Review

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2009;9(1):18-21.
Published online July 10, 2009.

Current Status and Strategy of Helicobacter pylori Eradication

헬리코박터 파일로리 제균 현황 및 전략

김상균ㆍ김진일*

서울대학교 의과대학 내과학교실, 간연구소, 가톨릭대학교 의과대학 내과학교실*

Abstract

Helicobacter pylori (H. pylori) is known to be associated with chronic gastritis, peptic ulcer, gastric MALT lymphoma and gastric cancer. Eradication of H. pylori can reduce recurrence of peptic ulcer, and is highly recommended for peptic ulcer disease. In cases of gastric MALT lymphoma, endoscopic or surgical resection of early gastric cancer, family history of gastric cancer and atrophic gastritis, eradication of H. pylori is possibly recommended in many consensus reports. In Korea, eradication of H. pylori has been recommended for peptic ulcer, low grade gastric MALT lymphoma and endoscopic resection of early gastric cancer. Recently, H. pylori infection rate has been reported to be 61.3% in Korea, and proton pump inhibitor-based eradication rate has declined under 85% due to increased antibiotics-resistance rate. Herein, current status of H. pylori eradication and management strategy would be discussed. (The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2009;9:18-21)

Key Words: Helicobacter pylori, Eradication, Strategy