Association between Oral Health and Gastric Neoplastic Lesions

Cha, Jae Hwang; Lee, Dong Won; Kim, Sinyoung; Kim, Jie Hyun; Moon, Ik Sang; Jung, Da Hyun; Park, Jae Jun; Youn, Young Hoon; Park, Hyojin

doi:2018.18.1.56

Korean J Helicobacter Up Gastrointest Res > Volume 18(1); 2018 > Article

Original Article

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2018;18(1):56-60.
DOI: https://doi.org/10.7704/kjhugr.2018.18.1.56 Published online March 10, 2018.

Association between Oral Health and Gastric Neoplastic Lesions

Jae Hwang Cha, Dong Won Lee, Sinyoung Kim, Jie Hyun Kim, Ik Sang Moon, Da Hyun Jung, Jae Jun Park, Young Hoon Youn, Hyojin Park

¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. otilia94@yuhs.ac
²Department of Periodontology, Yonsei University College of Dentistry, Seoul, Korea.
³Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
⁴Gangnam Severance Hospital, Seoul, Korea.

구강 위생과 위의 암성 병변과의 상관관계

차재황^1,4, 이동원^2,4, 김신영³, 김지현^1,4, 문익상^2,4, 정다현^1,4, 박재준^1,4, 윤영훈^1,4, 박효진^1,4

연세대학교 의과대학 내과학교실¹, 치과대학 치주과학교실², 의과대학 진단검사의학교실³, 강남세브란스병원⁴

Correspondence: Jie Hyun Kim, Tel: +82-2-2019-3505, Fax: +82-2-3463-3882,
Email: otilia94@yuhs.ac

Received: 27 July 2017 • Revised: 19 October 2017 • Accepted: 9 November 2017

Abstract

BACKGROUND/AIMS
Although several studies have suggested that tooth loss is associated with the risk of gastric cancer, the association between oral health and gastric cancer remains a controversial issue. Thus, we investigated whether oral health is associated with the risk of gastric neoplastic lesions. MATERIALS AND METHODS: We retrospectively evaluated 391 patients who underwent upper gastrointestinal endoscopic examination between March 2010 and February 2013. The tooth number and the age-related periodontal bone loss score (ArB score) were investigated as parameters of oral health. Gastric neoplastic lesions included adenomas and cancer detected on biopsy examination. RESULTS: We identified 10 patients (2.6%) with neoplastic lesions. Older age, a higher body mass index, and the presence of Helicobacter pylori infection were significantly associated with neoplastic lesions. However, there was no significant correlation about Kimura-Takemoto classification, ArB score, and tooth number. Multivariate analyses showed that age was significantly associated with neoplastic lesions. CONCLUSIONS: Our findings demonstrate that oral health (assessed using parameters such as tooth number and ArB score) may not be significantly associated with gastric neoplastic lesions.

Key Words: Bone loss; Helicobacter pylori; Oral health; Stomach neoplasms