Case Series of Gastric Hepatoid Adenocarcinoma

Myung, Yu Sik; Han, Jae Pil; Hong, Su Jin; Kim, Hye Soo; Park, Jung Hwan; Kim, Hee Kyung; Jeong, Gui Ae; Cho, Gyu Seok

doi:2015.15.1.53

Korean J Helicobacter Up Gastrointest Res > Volume 15(1); 2015 > Article

Case Report

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2015;15(1):53-58.
DOI: https://doi.org/10.7704/kjhugr.2015.15.1.53 Published online March 10, 2015.

Case Series of Gastric Hepatoid Adenocarcinoma

Yu Sik Myung, Jae Pil Han, Su Jin Hong, Hye Soo Kim, Jung Hwan Park, Hee Kyung Kim, Gui Ae Jeong, Gyu Seok Cho

¹Digestive Disease Center and Research Institute, Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea. rock5014@schmc.ac.kr
²Department of Pathology, Soonchunhyang University College of Medicine, Bucheon, Korea.
³Department of Surgery, Soonchunhyang University College of Medicine, Bucheon, Korea.

간세포양 위샘암종 증례

명유식, 한재필, 홍수진, 김혜수, 박정환, 김희경¹, 정귀애², 조규석²

순천향대학교 의과대학 내과학교실, 병리학교실¹, 외과학교실²

Abstract

Hepatoid adenocarcinoma of the stomach (HAS) is a rare form of gastric cancer that histologically resembles hepatocellular carcinoma and is characterized by large amounts of alpha fetoprotein in the serum. The prognosis of HAS is poor compared to that of primary gastric cancer with five-year survival rates of 9% and 44%, respectively. Here, we report five patients diagnosed with HAS. Our experience suggests that an advanced stage of HAS has an extremely poor prognosis, but early detection and radical surgery can help improve the prognosis of the disease.

Key Words: Alpha-fetoproteins; Stomach neoplasms; Hepatoid adenocarcinoma; Prognosis