Treatment of Adenocarcinoma of the Esophagogastric Junction |
So Yeon Kim, Kyoung Oh Kim |
Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea. kkoimge@naver.com |
위식도 접합부 암의 치료 |
김소연, 김경오 |
한림대학교성심병원 소화기내과 |
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Abstract |
In recent years, the incidence of adenocarcinoma of the esophagogastric junction (AEJ) is increasing in the western world, despite of decreasing trend of distal gastric cancer, and the prognosis of AEJ remains poor. The appropriate classification of AEJ is important for selecting the optimal surgical approach and making better prognosis. According to Siewert's classification, distal esophageal cancers (type I) are distinguished from true cardia cancers (type II) and subcardiac gastric cancers (type III). Until now, surgical resection with lymphadenectomy based on Siewert's classification has been the mainstay of treatment for all resectable AEJ. Except surgical approach, therapy strategies for AEJ include endoscopic ablation or endoscopic mucosal resection, endoscopic submucosal dissection, neoadjuvant or adjuvant therapy in combination with surgery, and palliative procedures such as stent, laser, photodynamic therapy. A multidisciplinary approach is necessary for optimal management of AEJ. In this article, we review the treatment options for AEJ including a tailored surgical approach. |
Key Words:
Adenocarcinoma of the esophagogastric junction; Surgery; Drug therapy; Radiotherapy; Endoscopic therapy |
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