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Korean J Helicobacter  Up Gastrointest Res > Volume 12(3); 2012 > Article
The Korean Journal of Helicobacter  and Upper Gastrointestinal Research 2012;12(3):151-157.
DOI: https://doi.org/10.7704/kjhugr.2012.12.3.151    Published online September 10, 2012.
Treatment of Adenocarcinoma of the Esophagogastric Junction
So Yeon Kim, Kyoung Oh Kim
Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea. kkoimge@naver.com
위식도 접합부 암의 치료
김소연, 김경오
한림대학교성심병원 소화기내과
Abstract
In recent years, the incidence of adenocarcinoma of the esophagogastric junction (AEJ) is increasing in the western world, despite of decreasing trend of distal gastric cancer, and the prognosis of AEJ remains poor. The appropriate classification of AEJ is important for selecting the optimal surgical approach and making better prognosis. According to Siewert's classification, distal esophageal cancers (type I) are distinguished from true cardia cancers (type II) and subcardiac gastric cancers (type III). Until now, surgical resection with lymphadenectomy based on Siewert's classification has been the mainstay of treatment for all resectable AEJ. Except surgical approach, therapy strategies for AEJ include endoscopic ablation or endoscopic mucosal resection, endoscopic submucosal dissection, neoadjuvant or adjuvant therapy in combination with surgery, and palliative procedures such as stent, laser, photodynamic therapy. A multidisciplinary approach is necessary for optimal management of AEJ. In this article, we review the treatment options for AEJ including a tailored surgical approach.
Key Words: Adenocarcinoma of the esophagogastric junction; Surgery; Drug therapy; Radiotherapy; Endoscopic therapy


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