Complications and Management of Peptic Ulcer Disease

Bang, Chang Seok; Baik, Gwang Ho

doi:2014.14.1.18

Korean J Helicobacter Up Gastrointest Res > Volume 14(1); 2014 > Article

Review

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2014;14(1):18-23.
DOI: https://doi.org/10.7704/kjhugr.2014.14.1.18 Published online March 10, 2014.

Complications and Management of Peptic Ulcer Disease

Chang Seok Bang, Gwang Ho Baik

Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea. baikgh@hallym.or.kr

소화성 궤양의 합병증과 대책

방창석, 백광호

한림대학교 의과대학 내과학교실

Abstract

Despite the improvement of medical managements of peptic ulcer and decline of Helicobacter pylori infection, complications of peptic ulcer are still prevalent in clinical practice. This is because of the increased use of ulcerogenic medications such as aspirin or non-steroidal anti-inflammatory drug (NSAID) in elderly patients. Peptic ulcer complications include bleeding, perforation, penetration and gastric outlet obstruction. These complications need to be managed by multidisciplinary approaches such as combination of endoscopic treatment, radiologic embolization, or surgical treatments. In addition to using proton pump inhibitors, H. pylori eradication and discontinuing ulcerogenic medications are essential in the prevention of recurrence. Although uncommon, non-H. pylori, non-NSAID ulcers should be suspected as a potential cause in recurrent cases of peptic ulcer complications.

Key Words: Peptic ulcer hemorrhage; Peptic ulcer perforation; Gastric outlet obstruction