A Case of Multiple Primary Cancer with Follicular Lymphoma

Park, Chan Seo; Lee, Si Hyung; Kim, Sung Bum; Park, Jun Suk; Kim, Sung Joon; Park, Joon Mo; Kang, Sung Hoon

doi:2014.14.1.61

Korean J Helicobacter Up Gastrointest Res > Volume 14(1); 2014 > Article

Case Report

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2014;14(1):61-66.
DOI: https://doi.org/10.7704/kjhugr.2014.14.1.61 Published online March 10, 2014.

A Case of Multiple Primary Cancer with Follicular Lymphoma

Chan Seo Park, Si Hyung Lee, Sung Bum Kim, Jun Suk Park, Sung Joon Kim, Joon Mo Park, Sung Hoon Kang

Department of Internal Medicine, Yeungnam University College of Medicine, Daegu, Korea. dr9696@nate.com

Abstract

The incidence of multiple primary cancer (MPC) is low but has been reported occasionally. Although follicular lymphoma is rare in Korea, the incidence is reported to be gradually increasing. We report a case of synchronous and metachronous MPC consisting of esophagus (squamous cell carcinoma), stomach (adenocarcinoma), and ampulla of Vater (extranodal follicular lymphoma grade 1) in a patient diagnosed as follicular lymphoma (grade 3a) six years ago. In a complicated case like ours, concurrent therapeutic control of synchronous MPC and metachronous hematological malignancy is challenging; meticulous examination and prioritized target therapy are essential for patients' survival.

Key Words: Multiple primary cancer; Squamous cell carcinoma; Adenocarcinoma; Follicular lymphoma