Negative Histology after Endoscopic Resection: How to Avoid It

Kwon, Yong Hwan

doi:2018.18.1.25

Korean J Helicobacter Up Gastrointest Res > Volume 18(1); 2018 > Article

Review

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2018;18(1):25-29.
DOI: https://doi.org/10.7704/kjhugr.2018.18.1.25 Published online March 10, 2018.

Negative Histology after Endoscopic Resection: How to Avoid It

Yong Hwan Kwon

Department of Internal Medicine, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Daegu, Korea. tear9754006@yahoo.co.kr

내시경 절제술 후 조직학적 음성 결과를 피하는 노하우

권용환

경북대학교 의과대학 경북대학교병원 내과학교실

Correspondence: Yong Hwan Kwon, Tel: +82-53-200-2609, Fax: +82-53-200-3089,
Email: tear9754006@yahoo.co.kr

Received: 30 December 2017 • Revised: 22 January 2018 • Accepted: 24 January 2018

Abstract

Endoscopic resection (ER) is the current standard of care for selected cases of gastric epithelial dysplasia or early gastric cancer because of its curative en bloc resectability and complete histopathological assessment of the specimen. Although ER provides many advantages to surgery, some adverse events, such as bleeding, perforation, and local recurrence, can occur during and after the procedure. Furthermore, negative pathological findings after ER cause concerns about the adequacy of the procedure and local recurrence after ER among endoscopists and patients. Several variant factors, such as complete removal of small gastric tumor lesions by using initial forceps biopsy, pathological inconsistencies between pathologists, and performing ER in the wrong area. Thus, endoscopists must consider these risk factors to avoid and manage negative pathological results.

Key Words: Endoscopic mucosal resection; Pathology; Stomach neoplasms