Endoscopic Diagnosis of Gastric MALT Lymphoma

Kang, Hye Won; Shim, Ki Nam

doi:2011.11.3.156

Korean J Helicobacter Up Gastrointest Res > Volume 11(3); 2011 > Article

Review

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2011;11(3):156-160.
DOI: https://doi.org/10.7704/kjhugr.2011.11.3.156 Published online December 10, 2011.

Endoscopic Diagnosis of Gastric MALT Lymphoma

Hye Won Kang, Ki Nam Shim

Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University School of Medicine, Seoul, Korea. shimkn@ewha.ac.kr

위 MALT 림프종의 내시경 진단

강혜원, 심기남

이화여자대학교 의학전문대학원 내과학교실

Abstract

Gastric mucosa-associated lymphoid tissue (MALT) lymphoma accounts for 2~7% of gastric malignancy, and its occurrence has been increasing. The connection between Helicobacter pylori (H. pylori) and gastric MALT lymphoma has been well established. In low grade gastric MALT lymphoma, H. pylori eradication can induce complete remission, so early detection is very important. However, endoscopic findings of MALT lymphoma are nonspecific and diagnosis is difficult by the naked eye due to various endoscopic appearances such as erosion, erythema, ulceration, atrophy and submucosal mass. Repeated deep tissue biopsies of the suspicious lesions and confirmation of the typical lymphoepithelial lesions is essential for diagnosis. Endoscopic ultrasound (EUS) can aid in accurate diagnosis, staging, and prediction of prognosis in gastric MALT lymphoma.

Key Words: Helicobacter pylori; MALT lymphoma