| Upper Gastrointestinal Hemorrhage from Esophageal Ulcer Caused by Coinfection of Herpes Simplex Virus and Cytomegalovirus in Immunocompromised Patient |
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Hoe Hoon Chung, Jae Young Jang, Ja Min Byun, Sun Hee Park, Dong Hyun Kim, Young Woon Chang |
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Department of Internal Medicine, College of Medicine, Kyung Hee University, Seoul, Korea. jyjang@khu.ac.kr |
| 면역기능이 저하된 환자에서 헤르페스바이러스 및 거대세포바이러스 동반 감염으로 발생한 식도 궤양에 의한 상부위장관 출혈 1예 |
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정회훈, 장재영, 변자민, 박선희, 김동현, 장영운 |
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경희대학교 의과대학 내과학교실 |
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| Abstract |
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Coinfection with herpes simplex virus and cytomegalovirus is a very rare cause of esophageal ulcer and upper gastrointestinal hemorrhage. A 26 year-old male kidney transplant recipient was referred with a complaint of melena. Upper gastrointestinal endoscopy showed a huge esophageal ulcer in the anastomosis site of the esophagogastrostomy. The ulcer occupied about two-thirds of the circumference of the esophageal lumen and an exposed vessel in the ulcer base was noted. Pathologic findings with immunohistochemical stain showed co-infection of herpes simplex virus and cytomegalovirus. He was treated successfully with endoscopic hemostasis and antiviral therapy. We report a case of upper gastrointestinal hemorrhage from esophageal ulcer caused by coinfection of herpes simplex virus and cytomegalovirus. |
| Key Words:
Esophageal ulcer; Simplexvirus; Cytomegalovirus; Gastrointestinal hemorrhage; Immunocompromised host |
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