| A Collision Tumor Comprising Early Gastric Adenocarcinoma and Diffuse Large B-cell Lymphoma after Endoscopic Gastric Submucosal Dissection |
|
Sang Sun Kim, Byeong Gwan Kim, A Young Cho, Seong Hee Lee, Hong Shik Shin, So Hee Yun, Jin Woong Cho, Myoung Jin Ju |
1Division of Gastroenterology, Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea. jeja-1004@daum.net
2Division of Gastroenterology, Department of Pathology, Presbyterian Medical Center, Jeonju, Korea. |
| 내시경 점막하 박리술을 시행한 환자에서 발견된 충돌성 조기위암과 거대 B세포 림프종 1예 |
|
김상선, 김병관, 조아영, 이성희, 신홍식, 윤소희, 조진웅, 주명진1 |
|
예수병원 소화기내과, 병리과1 |
|
|
| Abstract |
|
Concurrence of primary gastric adenocarcinoma and lymphoma have been described very rarely in the literature; its incidence is estimated at 0.08%. To our knowledge, there are no reports about a collision tumor comprising early gastric cancer and diffuse large B-cell lymphoma from the same lesion. The term "collision tumor" refers to the coexistence of two or more histologically distinct tumors within the same mass with no histologic admixture. A 76-year-old man complained of a 5-month-history of dyspepsia, and underwent esophagogastroduodenoscopy. Endoscopic findings showed a nodular, round, flat mass lesion in the upper body, therefore we performed endoscopic submucosal dissection (ESD). Pathologic findings revealed a well-differentiated adenocarcinoma accompanied by diffuse large B-cell lymphoma without evidence of Helicobacter pylori infection. Conventional CT and PET-CT scans revealed metastatic lymph nodes in the parotid gland, submandibular gland, maxillary gland and the inguinal regions. The pathogenesis of a collision tumor comprising two different cancers is not well understood. In addition, there are no established treatment guidelines in this series. In the current case, the patient underwent ESD for the removal of adenocarcinoma concomitantly with chemotherapy for the management of metastatic lymphoma. |
| Key Words:
Gastric adenocarcinoma; Lymphoma, large B-Cell, diffuse; Collision; Stomach neoplasms |
|
PDF Links
Full text via DOI
Download Citation
