A Case of Gastric Langerhans Cell Histiocytosis with Spontaneous Regression

Hwang, Keum Bit; Ham, Jun Soo; Hwang, Subin; Jung, Suk Hyeon; Lee, Jun Haeng

doi:2015.15.4.270

Korean J Helicobacter Up Gastrointest Res > Volume 15(4); 2015 > Article

Case Report

The Korean Journal of Helicobacter and Upper Gastrointestinal Research 2015;15(4):270-273.
DOI: https://doi.org/10.7704/kjhugr.2015.15.4.270 Published online December 10, 2015.

A Case of Gastric Langerhans Cell Histiocytosis with Spontaneous Regression

Keum Bit Hwang, Jun Soo Ham, Subin Hwang, Suk Hyeon Jung, Jun Haeng Lee

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. stomachlee@gmail.com

자연관해를 보인 위에 국한된 랑게르한스 세포 조직구증 1예

황금빛, 함준수, 황수빈, 정숙현, 이준행

성균관대학교 의과대학 삼성서울병원 내과

Abstract

A 44-year-old male was followed-up with esophagogastroduodenoscopy due to an esophageal submucosal tumor. On the lesser curvature of the gastric low body, a 0.5 cm sized round elevated lesion with hyperemia was noticed. Two pieces of biopsy were taken from this lesion for histopathologic examination. Histology showed Langerhans cell infiltration. Immunohistochemical staining was positive for CD1a antigen, which confirmed the diagnosis of Langerhans cell histiocytosis. There was no evidence of other organ involvement. The lesions spontaneously disappeared 4 months later without any treatment. We report a very rare case of gastric Langerhans cell histiocytosis.

Key Words: Langerhans cell histiocytosis; Neoplasm regression, spontaneous; Stomach; CD1a antigen